Drugs are used either as single
medicine or as combination in various diseases considering the prakriti of the
patient, condition of the disease. For this they are converted into different
forms. This process of modification can be termed as kalpana and altered form
of the dravya is called kalpa.
For convenience of study, kalpanas
are broadly classified into oushadha kalpana and ahara kalpana. Oushada kalpana
is mainly divided into five-Swarasa, Kalka, Kwatha, Sheetha and Phanta.
The potency of panchavidha
kashaya’s are in increasing order from phanta to swarasa.Scarcity
of raw materials in the fresh condition in each season and their varying
distribution throughout the localities made them to think of other means. For
preserving the fresh plant matter they dried and kept them for a long time
without altering the efficacy of active principles. Expression of juice was
found impracticable with some drugs and thus evolved the technology of
extraction using water.
By these methods, they isolated the
water soluble components in a successful way. Kwatha, Sheetha and phanta
kashaya’s were rapidly absorbed and onset of action was found to be quick.
These kashaya’s were prepared from single drugs or from a group of drugs. In the later case qualities of one drug could
modify, adapt or enhance the action of another to make it more favorable to the
state of the patient. Therefore kwatha
kalpana has more importance in clinical practice.
The term kwatha is basically derived from
the root word ‘kwathana’ which literally means process of boiling. Word kwatha
is derived from the root word ‘kwath nishpake’.
Shritha, Sheetha, Kashaya, Niruha are the
synonyms of Kwatha.
Kwatha is obtained by boiling the drugs in
water, with the help of fire. Kwatha plays an important role in ayurvedic
pharmaceutical technology because it is primary formulation for other kalpanas
like Sneha kalpana, Sandhana kalpana, Avaleha, Rasakriya.
Precautions to be taken while preparing kwatha
a) Drugs should be made into coarse powder.
b) Drugs should be boiled in earthen vessel.
c) Heating should be carried out only in
mild fire.
d) Vessel should be kept open throughout
the process of boiling.
General dosage:
The Kwatha has to be taken after digestion
of food in dwipala matra. 2 pala
As per AFI 1 Pala = 48 ml
The madhyama matra of kwatha is one pala.
But the strength of the patient and the intensity of the disease condition are
to be checked before deciding the dosage.
Different opinions regarding preparation of kwatha
Ancient texts describe different methods
for preparation of kwatha by which water is reduced to certain quantity.
According to Acharya Sarangdhara one pala of cleaned pounded drugs should be
bolied in 16 times of water in an earthern vessel and then reduced to 1/8 by
boiling under uniform heat. It is administered when it is warm.
This kwatha should be administered in a dose of 2 pala after the
complete digestion of food.
Depending on nature of drugs Acharya
Sarangadhara explains following method of kwatha preparation in sneha kalpana
adhyaya.
The quantity of water advised for mridu dravyas is 4 times that of
the drug, 8 times for katina and madhyama drugs,16 times water is mentioned for
athyantha katina drugs and is reduced to ¼ th.
According to Vagbhata kwatha is prepared by boiling 1 pala
of drug in 1/2 prastha water and reducing to 1/4th .
According to Sushrutha Samhitha kwatha is
prepared by taking bark, leaf, roots, of the drug or whole drug in a prescribed
quantity and dried in shade cut into small pieces by chedana, bhedana,
depending on the nature of the drug and added with eight times or sixteen times
water and boiled in a wide mouth pot, and reduced to 1/4th part by
boiling. Another method is
to boil one tula of raw drugs (like bark, leaves, fruits, roots) in 2 dronas of
water and reduced to ¼th.
In Ashtanga Sangraha kalpa sthana kwatha
preparation is metioned. It is almost similar to Sushrutha Samhitha. In this
water is to be added until the complete extraction occurs. i.e. raw drug become
muktarasa. The pot for preparing kwatha can be made up of copper, iron or mud.
The traditional method is to boil one pala
of drug in 16 times of water, reduce to ¼ and strain through a clean cloth,
strained liquid is again boiled and reduced to ½. (Thus a total reduction to
1/8 concentration occurs and 2 palas of kwatha will be obtained.)
According to bhaishajya ratnavali, kwatha
for bhavana can be prepared by boiling sufficient quantity of drugs in 8 times
of water and reducing to 1/8
For preparation of vamana kwatha, 4 pala of
drug is boiled in 64 pala of water and reduced to half.
According to vaidyaka paribhasha pradeepam,
1 anjali of water is boiled in 1 adaka of waterand reduced to 1/4th
(for preparation of yavagu)
Seven types of kwatha’s are mentioned in Hareetha Samhitha.
Table No.1 types of kwatha according to Hareetha Samhitha:
Type of kwatha
|
Water reduced to
|
Properties
|
1
|
Pachana
|
Water boiled and reduced to half
|
Ama dosha hara
|
2
|
Shodhana
|
Water boiled and reduced to1/12
|
Mala Shodaka
|
3
|
Kledana
|
Water boiled and reduced to ¼ th
|
Causes distress to heart.
|
4
|
Shamana
|
Water boiled and reduced to 1/8th
|
Reduces severity of doshas
|
5
|
Deepaneeya
|
Water boiled and reduced to 1/10
|
It stimulates digestion
|
6
|
Tharpana
|
Water just boiled
|
Nourishes dhathus
|
7
|
Vishoshi
|
Water boiled and reduced to 1/16
|
Causes thirst
|
Pachana kwatha should be given at night, shaman at the first part
of the day, deepana kwatha at noon and other three (kledana, soshana and
santharpana) at morning itself.
Table No.2 fourteen types of kwatha are described by Bhoja.
Sl. no
|
Name of kwatha
|
Quantity of water taken initially
|
Reduced to
|
1.
|
Sneha kashaya
|
4 times
|
1/4
|
2
|
Peya kashaya
|
8 times
|
1/8
|
3.
|
aschothana
|
On required
|
1/25
|
4.
|
asthapana
|
4 times
|
1/16
|
5.
|
Vrana prakshalana
|
8 times
|
1/12
|
6.
|
Vasthi kashaya
|
10 times
|
1/16
|
7.
|
Gandoosha kashaya
|
4 times
|
1/5
|
8.
|
Avagaha kashaya
|
10 times
|
1/4
|
9.
|
Paniya kashaya
|
4 times
|
1/4
|
10.
|
Snana salila kashaya
|
4 times
|
1/2
|
11.
|
Yavagu kashaya
|
4 times
|
1/2
|
12.
|
Vamana kashaya
|
4 times
|
1/2
|
13.
|
Parisheka kashaya
|
4 times
|
1/2
|
14.
|
Ushnodaka kashaya
|
4 times
|
1/2
|
When the prepared kwatha becomes black in
colour (Krishna or nila), viscous (Ghana), reddish (raktha) and in a state of
colloidal form (pichilam ) and when the soluble portion sediments (sithilam)
and also when flavour changes to kunapa gandha or visra gandha, it
can be said as substandard kwatha and is not fit for use.
When the kwatha is having the same Guna, Gandha and Varna of the
dravya by which it is formulated then such kwatha is good, pure and said as
amritopama.
Table No. 3 Quantity of water taken by different Acharyas
Reference Text
|
Drug
|
Water
|
Reduced to
|
Sharngadhara Samhita
|
1 Pala
|
16 times
|
1/8
|
Bhavaprakasha
|
1 Pala
|
16 times
|
1/8
|
Bhaishajya Ratnavali
|
½ Pala
|
16 times
|
1/8
|
Ashtanga Hrudaya
|
1 Pala
|
8 times
|
1/4
|
Sushruta Samhita
|
According to Yoga
|
8 to 16 times
|
1/4
|
Ashtanga Samgraha
|
1 pala
|
8 times
|
1/4
|
16 times (indu)
|
Sha. Sa.
|
Mrudu
|
4 times
|
1/4
|
Katina
|
8 times
|
Atyanta Katina
|
16 times
|
Anupana/prakshepa
1. The quantity of sugar and honey
depending on different disease conditions.
Table No. 4: Quantity of anupana used in different doshas
|
Vata vyadhi
|
Pitta vyadhi
|
Kaphaja vyadhi
|
sitha
|
1/4th
|
1/8th
|
1/16th
|
madhu
|
1/16th
|
1/8th
|
1/4th
|
2. Jeeraka Guggulu, Kshara, Saindhava,
Hingu, Trikatu Should Be Added In Dose
Of one sana.
3. Ksheera, Ghritha, Thaila, Mutra and
other dravyas should be added in a dose of one karsha.
Merits and demerits of Kwatha kalpana
Kwatha has got a versatile role among the
various medicinal preparations in use. Kwatha plays an important role in
ayurvedic pharmaceutical technology because it is the primary formulation for
other kalpanas like Snehakalpanas, Sandhana Kalpana, and Rasakriya. Kashaya’s
are one of the most commonly used kalpana in starting the treatment. It retains
many of the water soluble portions present in raw materials.
Water is an ideal substance since body is
constituted by more than 50 % of water. Water possesses the qualities like
deepana, tarpana, and is considered as
amrithopamam. Due to all these reasons, kashaya’s have much more important role
among kalpanas in ayurveda. A major part of therapeutic preparations mentioned
in the ancient texts are in the form of kashaya’s which are in daily practice. Kashaya’s
are widely used as bhavana dravya in many of drug purifications. Kashaya’s are
indicated as anupana in many conditions. Kashaya’s are used for vrana
prakshalana, niruha vasthi, and in netra kriyakarma’s.
Uses of kwatha with examples:
1) As a medicine
a) Maharasnadi kwatha in vatavyadhi
b) Pathya shadanga kwatha in siro roga
c) Phalathrikadi kwatha in kamala
2) As a bhavana dravya
a) Jiraka kwatha for ashtakshari gutika
b) Arjuna twak kwatha for prabhakara vati
c) Babbula kwatha for lavangadi vati
3) As an anupana
a) Triphala kwatha for kankayana gutika
b) Jiraka kwatha for kasthuryadi gulika
c) Bhunimba kwatha for dhanvatara gutika
4) To prepare other
drugs
a) Prasarini kwatha to prepare prasarini thaila
b) Arjuna tvak kwatha to prepare arjunarishta
c) Dashamula kwatha to prepare dashamularishta
5) As a sodhana dravya
a) Triphala kwatha for abhraka shodhana
b) Kulatha kwatha for vajra shodhana
c) Ela kwatha for karpura shilajathu
6) As marana dravya
a) Triphala kwatha for lohamarana
b) Kulatha kwatha for vajra marana
c) Kanchanara kwatha for swarna marana
Kwatha is an aqueous solution
containing the properties of substance or substances that have been processed
in it..The
purpose of herbal decoction is to extract the water-soluble constituents of
herbs by boiling. Quantum of heat and
duration of heating are prime concern for preparation of decoction. Soaking raw
materials result in softening, diffusion and osmosis of water into the raw materials
helps softening raw material through osmosis. Due to the presence of hydroxyl
group, the raw material swell, which results in the increased diffusion
pressure inside the cells, there by ultimately bursting of the cell wall.
Continuous heating and agitation during the preparation of decoction enhances
the extraction process by weakening the bonds and there by separating the
hydrophobic substances from hydrophilic substances. The water diffuses into the
raw material, dissolves the water soluble constituents and discharges it to the
liquid media due to collapse of the cell wall. Thus, transfer of water soluble
principle into the solvent (Water) is achieved.
Demerits of kwatha kalpana:
Apart from all these merits, kashaya’s have
some demerits also. Kashaya’s are prepared in aqueous media and this decreases
the stability of the product. Since water has wide solvent action it dissolves
wide range of substances. They may be medicinally inert and undesirable because
they readily ferment or decompose. Water dissolves glycosides, albumin, pectin,
colouring matters, sugar, tannin, mineral salts, and vegetable acids. In the
case of hot water, starch is also dissolved. They are favorable for the growth
of moulds and bacteria or bring about the decomposition of the product. The
presence of sugars or other carbohydrates result in alcoholic fermentation with
evolution of CO2 while the presence of protein matter leads to nitrogenous
fermentation, with liberation of ammonia.
Moreover, water promotes hydrolysis of many
substances and allows enzymatic action to take place. Exposure to atmosphere
and light accelerate spontaneous oxidation of the preparation. In kashaya,
oxidation results in unpleasant odour and taste and it becomes rancid. Moisture
accelerates the oxidation of volatile oils producing changes in quality of the
odour and increasing viscosity of kashaya. High humidity in tropical regions
contribute to the easy decomposition of contents, contamination, mould growth ,
fungal growth .So for a good result freshly prepared kashaya should be used to
get intended efficacy. Another demerit of kashaya is that a part of volatile
contents present in the raw materials are lost in course of preparation of
kwatha. Moreover alcohol and fat soluble contents cannot be extracted by these
methods.
Preservation of kashaya
Generally kwatha are to be consumed on the
same day as if kept for more than one day its natural smell, colour and taste
are found altered because of decomposition. Hence in ancient times either
decoction are made solid by further evaporating the liquid or moisture content
or making other types of preparations like sharkara and asasva arishtas. It
means ancient scholars used either sugar or self generated alcohol for the
preservation of decoction in liquid form or removing their moisture content by
evaporation.
In
modern science few chemical preservatives like benzoic acid, sodium benzoate,
are used in pharmacies for preservation of various kashaya’s. But the result is
a substantial reduction of original medicinal and nutritive value of drugs.
There are many brands of preservatives used to enhance shelf life and quantity
of addition in prepared medicine often surpasses the permissible limits. This
would cause deleterious effects on patient instead of being beneficial to him.